National Institute of Mental Health
A new study funded by the National Institute of Mental Health found a strong association between stressful life events and the development of major depression, but did not support the role of a particular gene variation previously thought to increase risk. A 2003 study had reported an increased risk for major depression among people with a particular gene variation who were exposed to a number of stressful life events over a five-year period. The new meta-analysis examined 14 studies that attempted to replicate the results of the 2003 study and found no association between the gene variant and major depression (alone or in conjunction with stressful life events) in any of the studies analyzed.
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.....from Weekly SPARK
